小林　謙也

助教

平成20年度入局

埼玉医科大学卒業

一言

“頭頸部がん”は全がんの５％で聞きなれない病気だと思います。丁寧な説明を心掛け、納得した治療を受けて頂けるように努めてまいります。

略歴

東大病院・がん研究会有明病院にて初期臨床研修後、東京大学耳鼻咽喉科に入局。NTT関東病院、竹田綜合病院、東大病院を経て、国立がん研究センター中央病院頭頸部外科及び希少がんセンター医員・医長として7年勤務。令和3年7月より現職。

専門

腫瘍外来にて頭頸部腫瘍の診療に従事し、手術は頭頸部悪性腫瘍を専門としている。研究分野は頭頸部腫瘍ゲノム学。次世代シーケンサーによるゲノム解析を中心としたトランスレーショナル研究を行っている。

所属学会

日本耳鼻咽喉科学会
日本頭頸部外科学会
日本頭頸部癌学会
日本頭蓋底外科学会
日本癌学会
日本唾液腺学会

資格、表彰

医学博士
日本耳鼻咽喉科学会認定専門医
日本耳鼻咽喉科学会認定指導医
頭頸部外科学会認定頭頸部がん専門医
頭頸部外科学会認定頭頸部がん指導医
日本がん治療認定医機構がん治療認定医
平成30年度　 国立がん研究センター　同窓会賞
令和元年度　　日本耳鼻咽喉科学会　研究奨励賞
令和6年度　　JJCO Awards, 2024 JJCO Paper of the Year (論文5.)

主要論文

  1. Kobayashi K, Yoshimoto S, Omura G, Matsumoto Y, Sakai A, Eguchi K, Sakai T, Honma Y, Matsumoto F, Kawazu M, Saito Y, Ryo E, Yoshida A, Yatabe Y, Mori T. An Institutional Experience of Core Needle Biopsy with Cooperative Implementation by Pathologists and Head and Neck Oncologists in Salivary Gland Carcinoma. Head Neck Pathol. 2024 In press
  2. Kobayashi K, Saito Y, Miyamoto S, Miyawaki S, Ito Y, Yamamura K, Kondo K. Meticulous Approach to Medial Palpebral Ligament in Lateral Rhinotomy; Avoiding Canthus Malposition. Laryngoscope. 2024 in press
  3. Kobayashi K, Saito Y, Kamogashira T, Kage H, Fukuoka O, Yamamura K, Mukai T, Oda K, Yamasoba T. Survival analysis of high-grade salivary gland carcinoma adjusted for length bias due to delay in comprehensive genomic profiling. Jpn J clin Oncol. 2023; 53(11):1092-1093.
  4. Kobayashi K, Kawazu M, Yoshimoto S, Ueno T, Omura G, Saito Y, Ando M, Ryo E, Sakyo A, Yoshida A, Yatabe Y, Mano H, Mori T. Genome doubling shapes high-grade transformation and novel EWSR1-LARP4 fusion shows distinct SOX10 immunostaining in hyalinizing clear cell carcinoma of salivary gland. Lab Invest. 2023;103(10):100213.
  5. Kobayashi K, Saito Y, Kage H, Fukuoka O, Yamamura K, Mukai T, Oda K, Yamasoba T. CDK12 alterations and ARID1A mutations are predictors of poor prognosis and therapeutic targets in high-grade salivary gland carcinoma: Analysis of the National Genomic Profiling Database. Jpn J clin Oncol. 2023;53(9):798-807.
  6. Kobayashi K, Hanai N, Yoshimoto S, Saito Y, Homma A. Current Topics and Management of Head and Neck Sarcomas. Jpn J clin Oncol. 2023;53(9):743-756.
  7. Kobayashi K, Ikeda A, Matsumoto Y, Matsumura S, Omura G, Eguchi K, Sakai A, Ito A, Mastumoto F, Yosimoto S. Surgical technique for super selective neck dissection under local anethesia in recurrent head and neck cancer. Head Neck. 2022; 44(8):1991-1994.
  8. Kobayashi K, Miyakita Y, Matsumoto F, Omura G, Matsumura S, Ikeda A, Eguchi K, Ito A, Narita Y, Akazawa S, Yoshimoto S. Olfactory preservation in craniofacial resection of tumor invading hemianterior skull base: operative video. J Neurol Surg B. 2021;83(Suppl 3):e639-e640.
  9. Kobayashi K, Yoshimoto S, Ando M, Matsumoto F, Murakami N, Omura G, Honma Y, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Ito A, Ryo E, Yatabe Y, Mori T. Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence. Oral Oncol. 2021;113:105091.
  10. Kobayashi K, Matsumoto F, Miyakita Y, Arikawa M, Omura G, Matsumura S, Ikeda A, Sakai A, Eguchi K, Narita Y, Akazawa S, Miyamoto S, Yoshimoto S. Risk factors for delayed surgical recovery and massive bleeding in skull base surgery. Biomed Hub. 2020;5(2):87-100.
  11. Kobayashi K, Matsumoto Y, Matsumoto F, Sato T, Mori T, Tsuchida T, Omura G, Matsumura S, Ikeda A, Sakai A, Eguchi K, Yoshimoto S. A surgical approach to schwannomas originating from the esophageal branch of the recurrent laryngeal nerve: Pictorial essay. Head Neck. 2019;41(11):4054-4059.
  12. Kobayashi K, Yoshimoto S, Matsumoto F, Ando M, Murakami N, Omura G, Fukasawa M, Matsumoto Y, Matsumura S, Akamatsu M, Hiraoka N, Eigitsu R, Mori T. All-exon TP53 sequencing and protein phenotype analysis accurately predict clinical outcome after surgical treatment of head and neck squamous cell carcinoma. Ann Surg Oncol. 2019;26(7):2294-2303.
  13. Kobayashi K, Matsumoto F, Miyakita Y, Mori T, Shimoi T, Murakami N, Yoshida A, Arakawa A, Omura G, Fukawasa M, Matsumoto Y, Matsumura S, Itami J, Narita Y, Yoshimoto S. Impact of Surgical Margin in Skull Base Surgery for Head and Neck Sarcomas. J Neurol Surg B. 2018;79(5):437-444.
  14. Kobayashi K, Mori T, Matsumoto F, Murakami N, Teshima M, Fukasawa M, Matsumoto Y, Matsumura S, Itami J, Asai M, Yoshimoto S. Impact of microscopic orbital periosteum invasion in orbital preservation surgery. Jpn J clin Oncol. 2017;47(4):321-327.
  15. Kobayashi K, Matsumoto F, Kodaira M, Mori T, Murakami N, Yoshida A, Maki D, Teshima M, Fukasawa M, Itami J, Asai M, Yoshimoto S. Significance of delayed primary excision in localized nonmetastatic adult head and neck rhabdomyosarcoma. Cancer Med. 2016;5(10):2708-2714.
  16. Kobayashi K, Ando M, Saito Y, Kondo K, Omura G, Shinozaki-Ushiku A, Fukayama M, Asakage T, Yamasoba T. Nerve Growth Factor Signals as Possible Pathogenic Biomarkers for Perineural Invasion in Adenoid Cystic Carcinoma. Otolaryngol Head Neck Surg. 2015;153(2):218-224.
  17. Kobayashi K, Saito Y, Omura G, Ando M, Sakamoto T, Yamasoba T, Asakage T. Clinical features of human papilloma virus-related head and neck squamous cell carcinoma of an unknown primary site. ORL J Otorhinolaryngol Relat Spec. 2014;76(3):137-146.
  18. Kobayashi K, Takenouchi S, Mitani H, Yoshida T. Recurrence Pattern after conservative surgery for papillary thyroid carcinoma. Auris Nasus Larynx. 2014;41(6):548-551.
  19. Kobayashi K, Nakao K, Kishishita S, Tamaruya N, Monobe H, Saito K, Kihara A. Vascular malformations of the head and Neck. Auris Nasus Larynx. 2013;40(1):89-92.
  20. Kobayashi K, Nakao K, Kawai K, Ito K, Hukumoto S, Asakage T, Oota S, Motoi R. Tumor-induced osteomalacia originating from the temporal bone: a case report. Head Neck. 2011;33(7):1072-1075.
  21. Kobayashi K, Nako K, Yoshida M, Ando M, Ebihara Y, Asakage T, Yamasoba T. Recurrent cancer of the parotid gland: how well dose salvage surgery work for locoregional failure? ORL J Otorhinolaryngol Relat Spec. 2009;71(5):239-243.