近藤健二
教授
平成６年入局
東京大学卒
ひとこと：すべての患者さんに「受診してよかった」と思っていただける診療を目標に努力しております。
略歴
1994年東京大学医学部医学科卒業。東京大学医学部附属病院耳鼻咽喉科、亀田総合病院耳鼻咽喉科で研修。
2001年東京大学大学院医学系研究科(耳鼻咽喉科学）修了。2001年より東京大学医学部附属病院耳鼻咽喉科助手。 2004年~2005年米国カリフォルニア大学サンディエゴ校耳鼻咽喉科博士研究員。
2006年4月より医局長。2008年5月より講師。2016年6月より准教授。2023年11月より現職。
専門
鼻科学、嗅覚医学、顔面神経疾患を専門とする。手術は内視鏡下鼻副鼻腔手術のほか耳、鼻、咽頭および頚部の疾患を担当している。 また加齢による嗅覚障害の病態生理の解明と治療法の開発、内耳神経の発生、再生機構の研究など、 基礎医学の成果を感覚器の臨床医学に応用すべく研究を行っている。
所属学会
１．日本耳鼻咽喉科学会 （学術委員、専門医）
２．日本鼻科学会（学会誌編集委員）
３．日本耳鼻咽喉科免疫アレルギー学会
４．日本顔面神経学会
５．日本耳科学会
６．日本頭頸部外科学会
７. 日本味と匂学会
８. Association for Research in Otolaryngology Active Member
主な論文
顔面神経
Kondo K, Takeuchi N, Tojima H, Ito K, Yamasoba T: Reconstruction of the intratemporal facial nerve using interposition nerve graft: time course of recovery in facial movement and electrophysiological findings. Acta Otolaryngol 127: supplement 559, 85-90, 2007.
Ushio M, Kondo K, Takeuchi N, Tojima H, Yamaguchi T, Kaga K: Prediction of the prognosis of Bell’s palsy using multivariate analyses. Otol Neurotol 29 :69-72, 2008.
Takanami T, Kondo K, Asakage T: Facial paralysis after superselective intraarterial chemotherapy via the middle meningeal artery in maxillary cancer. Auris Nasus Larynx 36: 479-81, 2009
Kanaya K, Ushio M, Kondo K, Hagisawa M, Suzukawa K, Yamaguchi T, Tojima H, Suzuki M, Yamasoba T: Recovery of facial movement and facial synkinesis in Bell’s palsy patients. Otol Neurootol 30: 640-644, 2009
Baba S, Kondo K, Kanaya K, Ushio M, Tojima H, Yamasoba T: Bell’s palsy in children: relationship between electroneurography findings and prognosis in comparison with adults. Otol Neurotol 32: 1554-8, 2011
Iwamura H, Kondo K, Sawamura H, Baba S, Yasuhara K, Yamasoba T: Amblyopia Associated with Congenital Facial Nerve Paralysis. ORL J Otorhinolaryngol Relat Spec 78:105-10, 2016
Nishijima H, Kondo K, Kagoya R, Iwamura H, Yasuhara K, Yamasoba T: Facial nerve paralysis associated with temporal bone masses. Auris Nasus Larynx 44: 548-553, 2017
Baba S, Kondo K, Yamasoba T: Electrophysiological Evaluation of the Facial Muscles in Congenital Unilateral Lower Lip Palsy. Otol Neurotol 39:106-110, 2018
Yoshihara S, Suzuki S, Yamasoba T, Kondo K: Recurrent facial palsy: The prognostic value of electrophysiological tests according to recurrence interval. Auris Nasus Larynx 47: 105-1010, 2019
Baba S, Kondo K, Yoshitomi A, Kanemaru A, Nakaya M, Yamasoba T: Efficacy of Mirror Biofeedback Rehabilitation on Synkinesis in Acute Stage Facial Palsy in Children. Otol Neurotol 42: e936-e941, 2021
慢性副鼻腔炎、アレルギー性鼻炎
Baba S, Kondo K, Kanaya K, Suzukawa K, Ushio M, Urata S, Asakage T, Kakigi A, Suzukawa M, Ohta K, Yamasoba T: Expression of IL-33 and its receptor ST2 in chronic rhinosinusitis with nasal polyps. Laryngoscope 124: 115-22, 2014
Yoshihara S, Kondo K, Kanaya K, Suzukawa K, Baba S, Toma-Hirano M, Kikuta S, Iwasaki Y, Fujio K, Yamasoba T: Tumour necrosis factor inhibitor-associated sinusitis. Rhinology 52:246-51, 2014
Baba S, Kondo K, Toma-Hirano M, Kanaya K, Suzukawa K, Ushio M, Suzukawa M, Ohta K, Yamasoba T: Local increase in IgE and class switch recombination to IgE in nasal polyps in chronic rhinosinusitis. Clin Exp Allergy 44:701-12, 2014
Kagoya R, Kondo K, Baba S, Toma-Hirano M, Nishijima H, Suzukawa K, Kikuta S, Yamasoba T: Correlation of basophil infiltration in nasal polyps with the severity of chronic rhinosinusitis. Ann Allergy Asthma Immunol 114:30-5, 2015
Suzuki S, Yasunaga H, Matsui H, Fushimi K, Kondo K, Yamasoba T: Complication rates after functional endoscopic sinus surgery: analysis of 50,734 Japanese patients. Laryngoscope 125:1785-91, 2015
Baba S, Kagoya R, Kondo K, Suzukawa M, Ohta K, Yamasoba T: T-cell phenotypes in chronic rhinosinusitis with nasal polyps in Japanese patients. Allergy Asthma Clin Immunol 19;11:33. eCollection 2015.
Nishijima H, Kondo K, Toma-Hirano M, Iwasaki S, Kikuta S, Fujimoto C, Ueha R, Kagoya R, Yamasoba T: Denervation of nasal mucosa induced by posterior nasal neurectomy suppresses nasal secretion, not hypersensitivity, in an allergic rhinitis rat model. Lab Invest 96: 981-93, 2016
Nishijima H, Kondo K, Toma-Hirano M, Kikuta S, Ando M, Ueha R, Yamasoba T: Prolonged denervation induces remodeling of nasal mucosa in rat model of posterior nasal neurectomy. Int Forum Allergy Rhinol 7: 670-678, 2017
Baba S, Kondo K, Suzukawa M, Ohta K, Yamasoba T. Distribution, subtype population, and IgE positivity of mast cells in chronic rhinosinusitis with nasal polyps. Ann Allergy Asthma Immunol 119: 120-128, 2017.
Nishijima H, Suzuki S, Kondo K, Yamasoba T, Yanagimoto S: Environmental factors associated with allergic rhinitis symptoms in Japanese university students: A cross-sectional study. Auris Nasus Larynx 45:1006-1013, 2018
Kagoya R, Kondo K, Kishimoto-Urata M, Shimizu Y, Kikuta S, Yamasoba T. A murine model of eosinophilic chronic rhinosinusitis using the topical application of a vitamin D3 analog. Allergy 76:1432-1442, 2021
嗅覚
Kondo K, Watanabe K, Sakamoto T, Suzukawa K, Nibu K, Kaga K, Yamasoba T: Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman’s glands in mouse olfactory mucosa: age-related progression. Cell Tissue Res 335:489-503, 2009
Kondo K, Suzukawa K, Sakamoto T, Watanabe K, Kanaya K, Ushio M, Yamaguchi T, Nibu K, Kaga K, Yamasoba T: Age-related changes in cell dynamics of the postnatal mouse olfactory neuroepithelium: cell proliferation, neuronal differentiation and cell death. J Comp Neurol 518: 1962-1975, 2010
Suzukawa K, Kondo K, Kanaya K, Sakamoto T, Watanabe K, Ushio M, Kaga K, Yamasoba T. Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage. J Comp Neurol 519: 2154-74, 2011
Kanaya K, Kondo K, Suzukawa K, Sakamoto T, Kikuta S, Okada K, Yamasoba T: Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly(I:C). Cell Tissue Res 357:279-99, 2014
Ueha R, Ueha S, Kondo K, Sakamoto T, Kikuta S, Kanaya K, Nishijima H, Matsushima K, Yamasoba T: Damage to Olfactory Progenitor Cells Is Involved in Cigarette Smoke-Induced Olfactory Dysfunction in Mice. Am J Pathol 186:579-86, 2016
Nishijima H, Kondo K, Nomura T, Yamasoba T: Ethmoidectomy combined with superior meatus enlargement increases olfactory airflow. Laryngoscope Investig Otolaryngol 2:136-146, 2017
Nishijima H, Kondo K, Yamamoto T, Nomura T, Kikuta S, Shimizu Y, Mizushima Y, Yamasoba T: Influence of the location of nasal polyps on olfactory airflow and olfaction. Int Forum Allergy Rhinol 8: 695-706, 2018
Iwamura H, Kondo K, Kikuta S, Nishijima H, Kagoya R, Suzukawa K, Ando M, Fujimoto C, Toma-Hirano M, Yamasoba T: Caloric restriction reduces basal cell proliferation and results in the deterioration of neuroepithelial regeneration following olfactotoxic mucosal damage in mouse olfactory mucosa. Cell Tissue Res 378: 175-193, 2019
Ijichi C, Wakabayashi H, Sugiyama S, Ihara Y, Nogi Y, Nagashima A, Ihara S, Niimura Y, Shimizu Y, Kondo K, Touhara K: Metabolism of Odorant Molecules in Human Nasal/Oral Cavity Affects the Odorant Perception. Chem Senses 44: 464-481, 2019
Kondo K, Kikuta S, Ueha R, Suzukawa K, Yamasoba T: Age-Related Olfactory Dysfunction: Epidemiology, Pathophysiology, and Clinical Management. Front Aging Neurosci 12:208, 2020
Ijichi C, Wakabayashi H, Sugiyama S, Hayashi K, Ihara Y, Nishijima H, Touhara K, Kondo K. Odorant metabolism of the olfactory cleft mucus in idiopathic olfactory impairment patients and healthy volunteers. Int Forum Allergy Rhinol 12: 293-301, 2022
Kagoya R, Toma-Hirano M, Yamagishi J, Matsumoto N, Kondo K, Ito K. Immunological status of the olfactory bulb in a murine model of Toll-like receptor 3-mediated upper respiratory tract inflammation. J Neuroinflammation 19: 13, 2022
Kishimoto-Urata M, Urata S, Kagoya R, Imamura F, Nagayama S, Reyna RA, Maruyama J, Yamasoba T, Kondo K, Hasegawa-Ishii S, Paessler S. Prolonged and extended impacts of SARS-CoV-2 on the olfactory neurocircuit. Sci Rep 12: 5728, 2022
Nishijima H, Zunitch MJ, Yoshida M, Kondo K, Yamasoba T, Schwob JE, Holbrook EH. Rapid fluorescent vital imaging of olfactory epithelium. iScience 25:104222, 2022